Understanding Nonlinear Mixed Effects Modeling for Population
Pharmacokinetics
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Documentation for package ‘nmw’ version 0.3.0
Help Pages
| nmw-package | Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics |
| AddCox | Add a Covariate Column to an Existing NONMEM dataset |
| AddDoNoTaLD | Add Dose Number, Time of Latest Dose, and Time after Latest Dose |
| AddPage | Add a New Page to PDF |
| add_crcl_cg | Add CRCL Column via Cockcroft-Gault |
| BtwTagMat | Extract Matrix from NONMEM XML Output |
| BtwTagVals | Extract Vector of Values Between XML Tags |
| build_dose_records | Build NONMEM Dose Records |
| build_nm_dataset | Build a NONMEM-Format Dataset from DM/EX/PC |
| build_obs_records | Build NONMEM Observation Records |
| ClosePDF | Close PDF Output |
| code_race | Code RACE as Integer |
| code_sex | Code SEX as Integer |
| CombDmExPc | Combine the demographics(DM), dosing(EX), and DV(PC) tables into a new NONMEM dataset |
| CovStep | Covariance Step |
| crcl_cg | Cockcroft-Gault Creatinine Clearance |
| dat2_time_to_posix | Combine Date and Time Strings into POSIXct |
| DxPlotPost | Diagnostic Plot for Post-Processing |
| EBEpair | EBE Pair Plot |
| EstStep | Estimation Step |
| ExpandDoseHist | Expand Dose History with ADDL/II Records |
| GetAICc | Get Corrected AIC (AICc) |
| GetCountEps | Get Count of Epsilons |
| GetCountEta | Get Count of Etas |
| GetCountObs | Get Count of Observations |
| GetCountPara | Get Count of Parameters |
| GetEstMethod | Get Estimation Method |
| GetOFV | Get Objective Function Value |
| InitStep | Initialization Step |
| locf_value | LOCF / LOCB Lookup |
| LogDV | Check if Model Uses Log-Transformed DV (from Control File) |
| LogDV2 | Check if Model Uses Log-Transformed DV (from FSUBS) |
| merge_cov_locf | Merge Time-Varying Covariates by LOCF |
| MinSuccess | Check Minimization Success |
| mlr2 | Multiple Linear Regression with Influence Diagnostics |
| NMIDStat | NONMEM Individual (ID) Statistics |
| NMVarStat | NONMEM Variable Statistics |
| nmw | Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics |
| nmw_report_ebe | Generate EBE Diagnostics Report (S5-EBE.PDF) |
| nmw_report_indipk | Generate Individual PK Parameter Report (SC-IndiPK.PDF) |
| nmw_report_input | Generate Input Data Summary Report (SA-Input.PDF) |
| nmw_report_ofv | Generate OFV Diagnostic Report (S1-OFV.PDF) |
| nmw_report_output | Generate NONMEM Output Report (SB-Output.PDF) |
| nmw_report_param | Generate Parameter Estimates Report (S2-Parameters.PDF) |
| nmw_report_pred | Generate Prediction Diagnostics Report (S3-Predictions.PDF) |
| nmw_report_resid | Generate Residual Diagnostics Report (S4-Residuals.PDF) |
| nmw_run | Run All NONMEM Post-Processing Reports |
| nm_to_molar | Convert NM Dataset from Mass to Molar Units |
| Outline | Draw Model Development Flow Diagram |
| ParseOut | Parse Value After Tag from NONMEM Output |
| parse_dtc | Parse SDTM-Style DTC Strings into POSIXct |
| PrepPDF | Prepare PDF Output |
| PrinMTxt | Print Multiple Lines of Text |
| PrinTxt | Print Text at Position |
| RemoveNA | Remove Rows with NA Values |
| ResTest | Residual Count Test Using Binomial Distribution |
| run.test.nm | Runs Test for NONMEM Residuals |
| SESuccess | Check Standard Error Success |
| SumOut | Summarize Multiple NONMEM Runs |
| TabStep | Table Step |
| TrimOut | Trimming and beautifying NONMEM original OUTPUT file |