Package: trialr
Version: 0.1.6
Date: 2023-03-11
Title: Clinical Trial Designs in 'rstan'
Description: A collection of clinical trial designs and methods, implemented in 
    'rstan' and R, including: the Continual Reassessment Method by O'Quigley et 
    al. (1990) <doi:10.2307/2531628>; EffTox by Thall & Cook (2004) 
    <doi:10.1111/j.0006-341X.2004.00218.x>; the two-parameter logistic method of
    Neuenschwander, Branson & Sponer (2008) <doi:10.1002/sim.3230>; and the 
    Augmented Binary method by Wason & Seaman (2013) <doi:10.1002/sim.5867>; and
    more. We provide functions to aid model-fitting and analysis. 
    The 'rstan' implementations may also serve as a cookbook to anyone looking 
    to extend or embellish these models. We hope that this package encourages 
    the use of Bayesian methods in clinical trials. There is a preponderance of 
    early phase trial designs because this is where Bayesian methods are used 
    most. If there is a method you would like implemented, please get in touch.
Authors@R: c(
  person("Kristian", "Brock", 
         email = "kristian.brock@gmail.com", 
         role = c("aut", "cre"),
         comment = c(ORCID = "0000-0002-3921-0166")),
  person("Trustees of", "Columbia University", 
         role = "cph"))
Maintainer: Kristian Brock <kristian.brock@gmail.com>
License: GPL (>= 3)
Encoding: UTF-8
ByteCompile: true
Depends: R (>= 3.5.0), methods,Rcpp (>= 1.0.1)
Imports: rstan (>= 2.18.2), rstantools (>= 1.5.1), rlang (>= 0.4.5),
        dplyr, purrr, magrittr, stringr, ggplot2, gtools, coda,
        tidybayes (>= 2.0.3), tibble (>= 3.0.0), binom, MASS
LinkingTo: StanHeaders (>= 2.18.1), rstan (>= 2.18.2), BH (>=
        1.69.0-1), Rcpp (>= 1.0.1), RcppEigen (>= 0.3.3.5.0),
        RcppParallel (>= 5.0.2)
SystemRequirements: GNU make
NeedsCompilation: yes
RoxygenNote: 7.1.2
VignetteBuilder: knitr
URL: https://github.com/brockk/trialr
BugReports: https://github.com/brockk/trialr/issues
Suggests: testthat, knitr, rmarkdown, tidyr, ggridges, DiagrammeR
Packaged: 2023-03-11 15:48:13 UTC; k
Author: Kristian Brock [aut, cre] (<https://orcid.org/0000-0002-3921-0166>),
  Trustees of Columbia University [cph]
Repository: CRAN
Date/Publication: 2023-03-12 11:00:02 UTC
Built: R 4.6.0; x86_64-w64-mingw32; 2026-03-10 05:04:32 UTC; windows
Archs: x64
