Package: SpaCCI
Type: Package
Title: Spatially Aware Cell-Cell Interaction Analysis
Version: 1.0.4
Date: 2025-05-12
Authors@R: person(given = "Li-Ting",
                  family = "Ku",
                  role = c("aut", "cre"),
                  email = "lku@mdanderson.org")
Maintainer: Li-Ting Ku <lku@mdanderson.org>
Description: Provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like 'CellChat' <http://www.cellchat.org/>, 'CellPhoneDB' <https://www.cellphonedb.org/>, 'Cellinker' <https://www.rna-society.org/cellinker/index.html>, 'ICELLNET' <https://github.com/soumelis-lab/ICELLNET>, and 'ConnectomeDB' <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales. 
License: GPL (>= 2)
Encoding: UTF-8
Depends: R (>= 3.5.0)
Imports: Rcpp (>= 1.0.13), Seurat (>= 4.0.0), nnls, ggrepel, pheatmap,
        circlize (>= 0.4.12), Matrix, dplyr, patchwork, grDevices,
        reshape2, graphics, ggplot2, FNN
LinkingTo: Rcpp, RcppArmadillo
RoxygenNote: 7.3.2
NeedsCompilation: yes
Packaged: 2025-05-12 17:40:17 UTC; lku
Author: Li-Ting Ku [aut, cre]
Repository: CRAN
Date/Publication: 2025-05-12 18:30:05 UTC
Built: R 4.5.2; x86_64-w64-mingw32; 2026-01-23 04:40:37 UTC; windows
Archs: x64
