To remove twistranet, launch at command prompt

  $ pip uninstall Twistranet

Answer 'yes' at prompt  

If you don't need it anymore, you can also remove all dependencies,
(Django, django-piston, django haystack, django-debug-toolbar)

  $ pip uninstall Django
  $ pip uninstall django-piston
  ...

Note :
=====

Uninstalling Twistranet will not destroy any data, since your
project is stored in another place.


 